HEALTH
Medical Breakthrough: Low-Cost Antidepressant Found to Combat Long COVID Fatigue
Researchers find that the low-cost antidepressant fluvoxamine significantly reduces fatigue in long COVID patients, offering a major breakthrough for millions.

A Major Advance in Long COVID Treatment
A global research team co-led by McMaster University has announced a significant breakthrough in the treatment of long COVID, identifying one of the first medications proven to meaningfully reduce persistent fatigue. According to a randomized, placebo-controlled clinical trial published in the Annals of Internal Medicine, the widely available antidepressant fluvoxamine significantly improved both energy levels and the overall quality of life for patients struggling with the long-term effects of the virus.
Fatigue remains the most debilitating symptom for the estimated 65 million people living with long COVID worldwide. For many, the exhaustion is so profound that it prevents them from returning to work or engaging in daily family activities. Despite the scale of the crisis, medical guidelines have largely been limited to supportive care and pacing due to a lack of evidence-based pharmacological options.
The REVIVE-TOGETHER Trial Results
The study, known as the REVIVE-TOGETHER trial, involved 399 adults in Brazil who had experienced persistent fatigue for at least 90 days following a COVID-19 infection. Participants were randomly assigned to receive either fluvoxamine, the diabetes medication metformin, or a placebo for 60 days. The results were stark: researchers found a 99 percent probability that fluvoxamine outperformed the placebo in reducing fatigue. Conversely, while metformin has previously shown promise in preventing long COVID if taken during the initial infection, it offered no meaningful benefit for those with established fatigue symptoms.
“This is an important step forward for patients who have been desperate for evidence-based options,” said Edward Mills, senior author and professor at McMaster University. He noted that because fluvoxamine is already widely used and well-understood by the medical community, it has immediate potential for clinical application.
Innovation in Clinical Research
Beyond the discovery of the drug’s efficacy, the trial was notable for its sophisticated Bayesian adaptive design. This allowed the international team—comprising researchers from Stanford, UBC, Duke, and several Brazilian institutions—to reach conclusions more efficiently than traditional trials. The study was able to stop specific treatment arms once the evidence became clear, accelerating the delivery of much-needed data to the public.
While experts emphasize that long COVID is a complex condition that may require multiple treatment pathways, the identification of fluvoxamine provides clinicians with the first strong evidence for a medication that targets the condition’s most common symptom. Further research is expected to determine which specific patient profiles benefit most from the treatment.
HEALTH
BC Conservatives Promise Universal Health Care Coverage as Debate Over Doctor Shortages Intensifies
BC Conservatives commit to universal health care and keeping emergency rooms open while criticizing Premier David Eby’s health record and doctor shortages.
Conservative Party Responds to NDP Health Care Strategy
More than one million residents in British Columbia currently lack a family doctor, while emergency rooms across the province experienced nearly 2,400 closures over a two-year period. Amid these system pressures and record-long specialist wait times, the Conservative Party of BC is promising that residents will need only their health card to access care.
Party Commitments and Critique of Current Record
Lorne Doerkson made a commitment on October 5 to protect health care funding and maintain a universal, publicly funded system in British Columbia. The Conservatives stated that a future party government would keep emergency rooms open, recruit necessary doctors and nurses, and safeguard public health care.
Addressing the current administration, the Conservatives pointed out that Premier David Eby has held office for nearly four years and acknowledged 50-week wait times for surgery. The opposition criticized the NDP’s approach of taxing doctors to resolve staff shortages, adding that the Premier previously promised every resident a family doctor by the end of 2025. The party anticipated that the NDP would launch a fear-based campaign to draw attention away from its health care record.
COMMUNITY
A Mother’s Call for Kindness and Plasma Donation as Guilty Plea Expected in Son’s Death
Brandon Kazakoff is expected to plead guilty in the death of 15-year-old Tristan Seeger in Kelowna as his mother hosts a local memorial plasma drive.
Expected Court Appearance and Anticipated Guilty Plea
An accused driver is scheduled to appear at the Kelowna Law Courts at 9 a.m. on Oct. 13 for trial in connection with the death of 15-year-old Tristan Seeger. Crown prosecutors informed Tristan’s mother, Paule Seeger, that the accused, Brandon Michael Kazakoff, intends to enter a guilty plea on the first day of proceedings. Kazakoff was arrested and charged on Sept. 6, 2024, with dangerous driving causing death, failure to stop or remain at the scene, and assault with a weapon regarding Tristan’s homicide. Kazakoff was released on bail three days after his arrest.
Reflecting on the news of the expected plea, Seeger shared her mixed emotions ahead of entering the courtroom. “It took me a day or two to really process,” Seeger said. “Part of me was, leading up to this, thinking I really want him to plead out so we don’t have to go through this. But part of me also wanted him to sit there and listen to everything. Sit there with Tristan’s mom in the room and hear it.”
Remembering Tristan Through Community Support
The upcoming court proceedings fall near the anniversary of the incident. Tristan was hit by a vehicle near Ben Lee Park in Kelowna on Oct. 21, 2023, and died in the hospital the following day. The driver involved fled the scene. Seeger explained that medical blood donations gave her family crucial time to say goodbye while Tristan was hospitalized. To honor his memory, she organizes an annual blood and plasma donation drive, securing appointment slots for Tristan’s Team on Oct. 22 and 23 at Kelowna’s Plasma Donor Centre.
“Making sense of Tristan’s death does not mean a long prison sentence,” Seeger commented. “It’s doing things like donating plasma.” Seeger added that her focus remains on positive outcomes from her loss. “Help another person, that’s the stuff that should come out of this,” she stated. When asked about her message to the public, Seeger encouraged community unity: “In times like this when we can focus on the bad… be different, be kind, be gentle,” she said. “Choose the right thing and don’t let hate win.”
COMMUNITY
BC Conservatives Promise $50M Rural Healthcare Fund Amid ER Closures
BC Conservatives propose a $50-million emergency fund to target rural hospital ER closures and staffing shortages across British Columbia.
Conservative Plan Focuses on Rural ER Closures
Speaking outside 100 Mile District General Hospital on Monday, Oct. 5, Lorne Doerkson announced that a B.C. Conservative government would establish a $50-million emergency fund to support rural medical practices. Doerkson, the party’s interim leader and incumbent MLA for Cariboo-Chilcotin, said the funding aims to prevent closures and assist with recruitment.
During the campaign stop, Doerkson noted that the local emergency department had experienced 39 announced shutdowns throughout 2026, though last-minute locum coverage allowed Interior Health to reopen the facility on several of those occasions. Overall, the ER remained closed well over 30 times. Doerkson pledged to maintain approved 2026 healthcare funding levels, fast-track credentials for foreign-trained Canadian physicians, and recognize provincial medical qualifications automatically to aid frontline staffing.
Community Impact and NDP Response
Former Cariboo-Chilcotin MLA Donna Barnett joined Doerkson, emphasizing that local residents and seniors rely on the emergency room, with some traveling up to an hour and a half for care. Local resident Amber Vigh, whose nine-year-old son Carter died at the hospital from an asthma attack in 2023, also voiced support for keeping the facility open continuously.
In response, B.C. NDP leader David Eby and party representatives criticized the Conservative proposal, questioning how the party would fund its healthcare promises without making service cuts. The NDP pointed to their own strategy of funding system investments through a proposed tax on high earners and millionaires. Doerkson countered that the proposed tax could deter new physicians from moving to British Columbia or prompt current doctors to leave.
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